chronic graft versus host disease |
Disease ID | 1405 |
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Disease | chronic graft versus host disease |
Manually Symptom | UMLS | Name(Total Manually Symptoms:6) |
Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:9) C0314719 | dry eye | 10 C0027726 | nephrotic syndrome | 2 C0029166 | oral manifestations | 2 C0037284 | skin lesions | 2 C0006272 | bronchiolitis obliterans | 2 C0085655 | polymyositis | 2 C0027121 | myositis | 1 C0152025 | polyneuropathy | 1 C0009450 | infection | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
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(Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
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(Waiting for update.) |
All Snps(Total Genotypes:9) | |||||||||||||
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snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
rs1131012 | 22646485 | 5175 | PECAM1 | umls:C0867389 | BeFree | We evaluated the association of 4 SNPs in ICAM1 (rs5498), PECAM1 (rs668 and rs1131012) and SELL (rs2229569) genes with acute and chronic graft-versus-host disease (GvHD) and those experiencing transplant-related mortality (TRM) within 1 year among 425 allogeneic HCT recipient-donor pairs. | 0.001085767 | 2013 | PECAM1 | 17 | 64350416 | T | C |
rs12428930 | 21628416 | 10673 | TNFSF13B | umls:C0867389 | BeFree | In multivariate analyses, 4 recipient BAFF SNPs (rs16972217 [odds ratio = 2.72, P = .004], rs7993590 [odds ratio = 2.35, P = .011], rs12428930 [odds ratio2.53, P = .008], and rs2893321 [odds ratio = 2.48, P = .009]) were independent predictors of GVHD subtypes, adjusted for conventional predictors of cGVHD. | 0.000542884 | 2011 | TNFSF13B;LOC102724347 | 13 | 108287357 | A | C |
rs16972217 | 21628416 | 10673 | TNFSF13B | umls:C0867389 | BeFree | In multivariate analyses, 4 recipient BAFF SNPs (rs16972217 [odds ratio = 2.72, P = .004], rs7993590 [odds ratio = 2.35, P = .011], rs12428930 [odds ratio2.53, P = .008], and rs2893321 [odds ratio = 2.48, P = .009]) were independent predictors of GVHD subtypes, adjusted for conventional predictors of cGVHD. | 0.000542884 | 2011 | TNFSF13B;LOC102724347 | 13 | 108283099 | C | T |
rs1805410 | 20574454 | 142 | PARP1 | umls:C0867389 | BeFree | One SNP in PARP1 gene (rs1805410) was associated with a higher risk of chronic GVHD (RR: 1.81, 95% CI: 1.29-2.54, P=0.001). | 0.000271442 | 2010 | PARP1 | 1 | 226380964 | T | C |
rs2229569 | 22646485 | 5175 | PECAM1 | umls:C0867389 | BeFree | We evaluated the association of 4 SNPs in ICAM1 (rs5498), PECAM1 (rs668 and rs1131012) and SELL (rs2229569) genes with acute and chronic graft-versus-host disease (GvHD) and those experiencing transplant-related mortality (TRM) within 1 year among 425 allogeneic HCT recipient-donor pairs. | 0.001085767 | 2013 | SELL | 1 | 169704697 | G | T,A |
rs2893321 | 21628416 | 10673 | TNFSF13B | umls:C0867389 | BeFree | In multivariate analyses, 4 recipient BAFF SNPs (rs16972217 [odds ratio = 2.72, P = .004], rs7993590 [odds ratio = 2.35, P = .011], rs12428930 [odds ratio2.53, P = .008], and rs2893321 [odds ratio = 2.48, P = .009]) were independent predictors of GVHD subtypes, adjusted for conventional predictors of cGVHD. | 0.000542884 | 2011 | TNFSF13B;LOC102724347 | 13 | 108290686 | A | G |
rs5498 | 22646485 | 5175 | PECAM1 | umls:C0867389 | BeFree | We evaluated the association of 4 SNPs in ICAM1 (rs5498), PECAM1 (rs668 and rs1131012) and SELL (rs2229569) genes with acute and chronic graft-versus-host disease (GvHD) and those experiencing transplant-related mortality (TRM) within 1 year among 425 allogeneic HCT recipient-donor pairs. | 0.001085767 | 2013 | ICAM1;ICAM4;LOC105372272 | 19 | 10285007 | A | G |
rs668 | 22646485 | 5175 | PECAM1 | umls:C0867389 | BeFree | We evaluated the association of 4 SNPs in ICAM1 (rs5498), PECAM1 (rs668 and rs1131012) and SELL (rs2229569) genes with acute and chronic graft-versus-host disease (GvHD) and those experiencing transplant-related mortality (TRM) within 1 year among 425 allogeneic HCT recipient-donor pairs. | 0.001085767 | 2013 | NA | NA | NA | NA | NA |
rs7993590 | 21628416 | 10673 | TNFSF13B | umls:C0867389 | BeFree | In multivariate analyses, 4 recipient BAFF SNPs (rs16972217 [odds ratio = 2.72, P = .004], rs7993590 [odds ratio = 2.35, P = .011], rs12428930 [odds ratio2.53, P = .008], and rs2893321 [odds ratio = 2.48, P = .009]) were independent predictors of GVHD subtypes, adjusted for conventional predictors of cGVHD. | 0.000542884 | 2011 | TNFSF13B;LOC102724347 | 13 | 108283554 | A | T |
GWASdb Annotation(Total Genotypes:0) | |
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(Waiting for update.) |
GWASdb Snp Trait(Total Genotypes:0) | |
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(Waiting for update.) |
Mapped by lexical matching(Total Items:0) |
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(Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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(Waiting for update.) |
Disease ID | 1405 |
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Disease | chronic graft versus host disease |
Case | (Waiting for update.) |